56. Das, D.; Roy, G.; Mugesh, G.* Antithyroid Drug Carbimazole and Its Analogues: Synthesis and Inhibition of Peroxidase-Catalyzed Iodination of L-Tyrosine.
J. Med. Chem., 2008, 51, 7313 - 7317. Read more....

 

55. Sarma, B. K.; Mugesh, G.* Antioxidant Activity of the Anti-inflammatory Compound Ebselen: A Reversible Cyclization Pathway via Selenenic and Seleninic Acid Intermediates.
Chem. Eur. J., 2008, 14, 10603 - 10614. Read more....

 

54. Bhuyan, B. J.; Mugesh, G.* Heme Peroxidase-catalyzed Iodination of Human Angiotensins and the Effect of Iodination on Angiotensin Converting Enzyme Activity.
Inorg. Chem., 2008, 47, 6569 - 6571. Read more....

 

53. Tamilselvi, A.; Mugesh, G.* Zinc and Antibiotic Resistance: Metallo-b-lactamases and
their Synthetic Analogues.
J. Biol. Inorg. Chem., 2008, 13, 1039 - 1053. Read more....

 

52. Bhabak, K. P.; Mugesh, G.* A Simple and Efficient Strategy to Enhance the Antioxidant Activities of Amino-Substituted Glutathione Peroxidase Mimics.
Chem. Eur. J., 2008, 14, 8640 - 8651. Read more....

 

51. Sarma, B. K.; Mugesh, G.* Thiol Cofactors for Selenoenzymes and their Synthetic Mimics.
Org. Biomol. Chem., 2008, 6, 965 - 974. Read more....
[This article is one of the Top 10 Most Accessed articles during January - June 2008].
[This work has been featured inside Cover Page of the Journal]

 

50. Roy, G.; Mugesh, G.* Selenium Analogues of Anti-thyroid Drugs.
Phosph. Sulfur and Silicon, 2008, 183, 908 - 923. Read more....
[Invited article for a Special Issue on Organoselenium and Tellurium Compounds].

 

49. Jayaram, P. N.; Roy, G.; Mugesh, G.* Effect of Thione-Thiol Tautomerism on the Inhibition of Lactoperoxidase by Anti-thyroid Drugs and their Analogues.
J. Chem. Sci., 2008, 120, 143 - 154. Read more....
[Special Issue on Chemical Research Society of India - Tenth Anniversary].

 

48. Roy, G.; Mugesh, G.* Selenium Analogues of Anti-thyroid Drugs - Recent Developments.
Chemistry & Biodiversity, 2008, 5, 414 - 439. Read more....
[Invited article for a Special Issue].

 

47. Sarma, B. K.; Mugesh, G.* Redox Regulation of Protein Tyrosine Phosphatase 1B (PTP1B): A Biomimetic Study on the Unexpected Formation of a Sulfenyl Amide Intermediate.
J. Am. Chem. Soc., 2007, 129, 8872 - 8881. Read more....
[This work has also been featured in Mint (Hindustan Times Group) Newspaper]

 

46. Scholz, P.; Mugesh, G.; Ambrugger, P.; Schmutzler, C.; Koehrle, J. Effects of sulfur- and selenium-containing derivatives of MMI and PTU on type I 5'-deiodinase and thyroperoxidase.
Hormone Research, 2007, 68, 57 - 58.

 

45. Bhabak, K. P.; Mugesh, G.* Synthesis, Characterization and Antioxidant Activity of Some Ebselen Analogues.
Chem. Eur. J., 2007, 13, 4594 - 4601. Read more....

 

44. Roy, G.; Das, D.; Mugesh, G.* Bioinorganic Chemistry Aspects of the Inhibition of Thyroid Hormone Biosynthesis by Anti-hyperthyroid Drugs.
Inorg. Chim. Acta, 2007, 360, 303 - 316. Read more....
[Invited article for the Special Issue: Inorganic Chemistry - The Next Generation].
[Read the Preface to this special issue by the Editor of ICA]
[This paper has been cited in the Science Direct - TOP 25 Hottest Articles]

 

43. Tamilselvi, A.; Nethaji, M.; Mugesh, G.* Antibiotic Resistance: Mono- and Dinuclear Zinc Complexes as Metallo-beta-Lactamase Mimics.
Chem. Eur. J., 2006, 12, 7797 - 7806. Read more....
[This work has been featured on the Cover Page of the Journal]
[This paper has been listed as one of the Most Accessed articles in October 2006].

 

42. Roy, G.; Mugesh, G.* Thyroid Hormone Synthesis and Anti-thyroid Drugs: A Bioinorganic Chemistry Approach.
J. Chem. Sci., 2006, 118, 619 - 625.
[Invited Article for the Special Issue: Modern Trends in Inorganic Chemistry].

 

41. Roy, G.; Mugesh, G.* Bioinorganic Chemistry in Thyroid Gland: Effect of Antithyroid Drugs on Peroxidase-Catalyzed Oxidation and Iodination Reactions.
Bioinorg. Chem. Appln., 2006, Vol. 2006, 1 - 9. Read more....

 

40. Mishra, B.; Priyadarsini, K. I.; Mohan, H.; Mugesh, G.* Horseradish Peroxidase Inhibition and Antioxidant Activity of Ebselen and Related Organoselenium Compounds.
Bioorg. Med. Chem. Lett., 2006, 16, 5334 - 5338. Read more....

 

39. Roy, G.; Nethaji, M.; Mugesh, G.* Interaction of Anti-Thyroid Drugs with Iodine: The Isolation of Two Unusual Ionic Compounds Derived from Se-Methimazole.
Org. Biomol. Chem., 2006, 4, 2883 - 2887. Read more....
[This work has been featured on the Cover Page of the Journal]

 

38. Sarma, B. K.; Mugesh, G.* Biomimetic Studies on Selenoenzymes: Modeling the Role of Proximal Histidines in Thioredoxin Reductases.
Inorg. Chem., 2006, 45, 5307 - 5314. Read more....

 

37. Roy, G.; Nethaji, M.; Mugesh, G.* Bioinorganic Chemistry of Anti-Thyroid Drugs: An Unusual Formation of a Copper(II) Complex.
Inorg. Chem. Commun., 2006, 9, 571 - 574. Read more....
[This paper has been cited in the Science Direct - TOP 25 Hottest Articles]

 

36. Nicolaou, K. C., Chen, D, Y.-K., Li, Y., Uesaka, N., Petrovic, G., Koftis, T. V., Bernal, F., Frederick, M. O., Govindasamy, M., Ling, T., Pihko, P. M., Tang, W., Vyskocil, S. Total Synthesis and Structural Elucidation of Azaspiracid-1. Synthesis-Based Analysis of Originally Proposed Structures and Indication of Their Non-Identity to the Natural Product.
J. Am. Chem. Soc., 2006, 128, 2258 - 2267. Read more....

 

35. Roy, G.; Mugesh, G.* Anti-Thyroid Drugs and Thyroid Hormone Synthesis: Effect of Methimazole Derivatives on Peroxidase-Catalyzed Reactions.
J. Am. Chem. Soc., 2005, 127, 15207 - 15217. Read more....
[This work has been highlighted in the Down to Earth Science and Environment Magazine and The Statesman Newspaper]

 

34. Mishra, B., Priyadarsini, K. I., Mohan, H., Mugesh, G. Free Radical Scavenging and Peroxidase Activity of Ebselen Derivatives.
Free Rad. Biol. Med., 2005, 39, S14 - S14. Read more....

 

33. Kalai, T.; Mugesh, G.; Roy, G.; Sies, H.; Berente, Z.; Hideg, K. Combining Benzo[d]isoselenazol-3-ones with Sterically Hindered Alicyclic Amines and Nitroxides: Enhanced Activity as Glutathione Peroxidase Mimics.
Org. Biomol. Chem., 2005, 3, 3564 - 3569. Read more....

 

32. Sarma, B. K.; Mugesh, G.* Glutathione Peroxidase (GPx)-like Antioxidant Activity of the Organoselenium Drug Ebselen: Unexpected Complications with Thiol Exchange Reactions.
J. Am. Chem. Soc., 2005, 127, 11477 - 11485. Read more....

 

31. Roy, G.; Sarma, B. K.; Phadnis, P. P.; Mugesh, G.* Selenium-containing Enzymes in Mammals: Chemical Perspectives.
J. Chem. Sci., 2005, 117, 287 - 303. Read more....
[This paper has been featured on the Cover Page of the Journal].

 

30. Phadnis, P. P.; Mugesh, G.* Internally Stabilized Selenocysteine Derivatives: Syntheses, 77Se NMR and Biomimetic Studies.
Org. Biomol. Chem., 2005, 3, 2476 - 2481. Read more....

 

29. Roy, G.; Mugesh, G.* Chemistry in Thyroid Gland: Iodothyronine Deiodinases and Anti-thyroid Drugs.
Phosph. Sulfur and Silicon, 2005, 180, 891 - 902. Read more....

 

28. Wismach, C.; du Mont, W.-W.; Jones, P. G.; Ernst, L.; Papke, U.; Mugesh, G.; Kaim, W.; Wanner, M.; Becker, K. D. Selenol Nitrosation and Se-Nitrososelenol-Homolysis: a Reaction Path with Possible Biochemical Implications.
Angew. Chem. Int. Ed. 2004, 43, 3970 - 3974. Read more....

 

27. Roy, G.; Nethaji, M.; Mugesh, G.* Biomimetic Studies on Anti-thyroid Drugs and Thyroid Hormone Synthesis.
J. Am. Chem. Soc. 2004, 126, 2712 - 2713. Read more....